@article {1449, title = {Modeling the pharmacodynamics of nandrolone doping drug and implications for anti-doping testing}, journal = {System Dynamics Review}, volume = {36}, year = {2020}, pages = {467-496}, abstract = {

Abstract We model the pathways of nandrolone in the body, an anabolic steroid widely used as a performance enhancing drug (PED). The model generates the dynamics of nandrolone and its metabolites. PED tests check for the presence of a primary metabolite of nandrolone, 19-NA in urine. To cheat in these tests, PED users typically use inhibitors that reduce the urinary concentration of 19-NA. One such inhibitor is finasteride. Finasteride{\textquoteright}s main effect in the body is the inhibition of reductase enzymes that turn nandrolone into its metabolite 19-NA. To capture this effect, we include structures for finasteride and reductase enzymes in the model. The model is tested by fundamental structure validity tests. We also show that the model behavior is consistent with experimental data in the literature. We finally investigate the potential ways by which the drug users may cheat in PED tests and make suggestions for improved testing as counter-measures. {\textcopyright} 2021 System Dynamics Society

}, doi = {https://doi.org/10.1002/sdr.1672}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/sdr.1672}, author = {Sahin, {\"O}zge and Feyyaz {\c S}ent{\"u}rk and Yaman Barlas and Yasarcan, Hakan} } @article {1493, title = {The moderating impact of supply network topology on the effectiveness of risk management}, journal = {International Journal of Production Economics}, volume = {197}, year = {2018}, pages = {13-26}, abstract = {

While supply chain risk management offers a rich toolset for dealing with risk at the dyadic level, less attention has been given to the effectiveness of risk management in complex supply networks. We bridge this gap by building an agent based model to explore the relationship between topological characteristics of complex supply networks and their ability to recover through inventory mitigation and contingent rerouting. We simulate upstream supply networks, where each agent represents a supplier. Suppliers{\textquoteright} connectivity patterns are generated through random and preferential attachment models. Each supplier manages its inventory using an anchor-and-adjust ordering policy. We then randomly disrupt suppliers and observe how different topologies recover when risk management strategies are applied. Our results show that topology has a moderating effect on the effectiveness of risk management strategies. Scale-free supply networks generate lower costs, have higher fill-rates, and need less inventory to recover when exposed to random disruptions than random networks. Random networks need significantly more inventory distributed across the network to achieve the same fill rates as scale-free networks. Inventory mitigation improves fill-rate more than contingent rerouting regardless of network topology. Contingent rerouting is not effective for scale-free networks due to the low number of alternative suppliers, particularly for short-lasting disruptions. We also find that applying inventory mitigation to the most disrupted suppliers is only effective when the network is exposed to frequent disruptions; and not cost effective otherwise. Our work contributes to the emerging field of research on the relationship between complex supply network topology and resilience.

}, keywords = {Agent-based modelling, Complex supply networks, Contingent rerouting, Inventory mitigation, Random networks, Scale-free networks, Supply chain risk management}, issn = {0925-5273}, doi = {https://doi.org/10.1016/j.ijpe.2017.12.013}, url = {https://www.sciencedirect.com/science/article/pii/S092552731730419X}, author = {Anna Ledwoch and Yasarcan, Hakan and Alexandra Brintrup} } @article {1494, title = {Effect of Lead Time on Anchor-and-Adjust Ordering Policy in Continuous Time Stock Control Systems}, journal = {Korean System Dynamics Review}, volume = {2}, year = {2017}, month = {Jun}, pages = {65{\textendash}85}, author = {Mutallip, Ahmet and Yasarcan, Hakan} } @article {1495, title = {The Shifting the Burden Archetype A Workforce and Task Backlog Management Game}, journal = {Korean System Dynamics Review}, volume = {4}, year = {2017}, month = {Feb}, pages = {81{\textendash}110}, author = {G{\"u}ran, Seniha Zeynep and Yasarcan, Hakan} } @article {1496, title = {Results of a beer game experiment: Should a manager always behave according to the book?}, journal = {Complexity}, volume = {21}, year = {2016}, pages = {190-199}, abstract = {

We investigate the effect of the literature suggested optimal values of the parameters of a dynamic decision-making heuristic in the presence of semirationally managed supply chain echelons using a soft coded one-to-one version of The Beer Game as an experimental platform. According to the counterintuitive results obtained in this study, it is possible for a {\textquotedblleft}rational manager{\textquotedblright} to obtain higher costs than the costs generated by a {\textquotedblleft}semirational manager.{\textquotedblright} Thus, the results do not support the use of the well-established decision parameter values for the echelon of concern if the other echelons{\textquoteright} inventories are managed suboptimally. {\textcopyright} 2015 Wiley Periodicals, Inc. Complexity 21: 190{\textendash}199, 2016

}, keywords = {anchor-and-adjust heuristic, artificial agents, beer game, stock management, supply chain management}, doi = {https://doi.org/10.1002/cplx.21731}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/cplx.21731}, author = {Edali, Mert and Yasarcan, Hakan} } @conference {mutallip2014desired, title = {Desired Supply Line Value Calculation for Multi-Supplier Systems}, booktitle = {The 32nd International System Dynamics Conference, Delft, Netherlands}, year = {2014}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2014/index.html)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2014/index.html)}, author = {Mutallip, Ahmet and Yasarcan, Hakan} } @conference {mutallip2014effect, title = {Effect of Lead Time on Anchor-and-Adjust Ordering Policy in Continuous Time Stock Control Systems}, booktitle = {The 32nd International System Dynamics Conference, Delft, Netherlands}, year = {2014}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2014/index.html)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2014/index.html)}, author = {Mutallip, Ahmet and Yasarcan, Hakan} } @conference {edali2014effect, title = {The Effect of Semi-Rational Supply Chain Members on the Decision Parameters Used in Managing the Stock of an Echelon}, booktitle = {The 32nd International System Dynamics Conference, Delft, Netherlands}, year = {2014}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2014/index.html)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2014/index.html)}, author = {Edali, Mert and Yasarcan, Hakan} } @article {1497, title = {A Mathematical Model of the Beer Game}, journal = {Journal of Artificial Societies and Social Simulation}, volume = {17}, year = {2014}, pages = {2}, abstract = {

The beer production-distribution game, in short {\textquotedblleft}The Beer Game{\textquotedblright}, is a multiplayer board game, where each individual player acts as an independent agent. The game is widely used in management education aiming to give an experience to the participants about the potential dynamic problems that can be encountered in supply chain management, such as oscillations and amplification of oscillations as one moves from downstream towards upstream echelons. The game is also used in numerous scientific studies. In this paper, we construct a mathematical model that is an exact one-to-one replica of the original board version of The Beer Game. We apply model replication principles and discuss the difficulties we faced in the process of constructing the mathematical model. Accordingly, the model is presented in full precision including necessary assumptions, explanations, and units for all parameters and variables. In addition, the adjustable parameters are stated, the equations governing the artificial agents{\textquoteright} decision making processes are mentioned, and an R code of the model is provided. We also shortly discuss how the R code can be used in experimentation and how it can also be used to create a single-player or multi-player beer game on a computer. Our code can produce the exact same benchmark cost values reported by Sterman (1989) verifying that it is correctly implemented. The mathematical model and the R code presented in this paper aims to facilitate potential future studies based on The Beer Game.

}, keywords = {Acquisition Lag, artificial agents, beer game, Mathematical Model, Replication, System Dynamics}, issn = {1460-7425}, doi = {10.18564/jasss.2555}, url = {http://jasss.soc.surrey.ac.uk/17/4/2.html}, author = {Edali, Mert and Yasarcan, Hakan} } @article {edali2014mathematical, title = {A Mathematical Model of the Beer Game}, journal = {Journal of Artificial Societies and Social Simulation}, volume = {17}, number = {4}, year = {2014}, pages = {jasss{\textendash}soc}, publisher = {Journal of Artificial Societies and Social Simulation}, author = {Edali, Mert and Yasarcan, Hakan} } @conference {tanyolacc2012control, title = {Control Heuristics for Soft Landing Problem}, booktitle = {The 30th International System Dynamics Conference, St. Gallen, Switzerland}, year = {2012}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2012/index.html)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2012/index.html)}, author = {Tanyola{\c c}, Togay and Yasarcan, Hakan} } @conference {mutallip2012parametric, title = {A Parametric Analysis of the Effect of a Material Supply Line Delay in Stock Management}, booktitle = {The 30th International System Dynamics Conference, St. Gallen, Switzerland}, year = {2012}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2012/index.html)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2012/index.html)}, author = {Mutallip, Ahmet and Yasarcan, Hakan} } @conference {yasarcan2012soft, title = {A Soft Landing Model and an Experimental Platform as an Introductory Control Design Tool}, booktitle = {The 30th International System Dynamics Conference, St. Gallen, Switzerland}, year = {2012}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2012/index.html)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2012/index.html)}, author = {Yasarcan, Hakan and Tanyola{\c c}, Togay} } @conference {yasarcan2011information, title = {Information Sharing in Supply Chains: A Systemic Approach}, booktitle = {The 29th International System Dynamics Conference, Washington, DC, USA}, year = {2011}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2011/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2011/index.htm)}, author = {Yasarcan, Hakan} } @conference {tanyolacc2011soft, title = {A Soft Landing Model and a Mass Spring Damper Based Control Heuristic}, booktitle = {The 29th International System Dynamics Conference, Washington, DC, USA}, year = {2011}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2011/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2011/index.htm)}, author = {Tanyola{\c c}, Togay and Yasarcan, Hakan} } @article {yasarcan2011stock, title = {Stock management in the presence of significant measurement delays}, journal = {System Dynamics Review}, volume = {27}, number = {1}, year = {2011}, pages = {91{\textendash}109}, publisher = {Wiley Online Library}, author = {Yasarcan, Hakan} } @conference {cseker2010controlling, title = {Controlling the Direction of a Model Helicopter}, booktitle = {The 28th International System Dynamics Conference, Seoul, Korea}, year = {2010}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2010/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2010/index.htm)}, author = {Oylum {\c S}eker and Yasarcan, Hakan} } @conference {herdem2010dynamics, title = {Dynamics of Glucose-Insulin Regulation: Insulin Injection Regime for Patients with Diabetes Type 1}, booktitle = {The 28th International System Dynamics Conference, Seoul, Korea}, year = {2010}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2010/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2010/index.htm)}, author = {Herdem, Canan and Yasarcan, Hakan} } @article {yasarcan2010improving, title = {Improving understanding, learning, and performances of novices in dynamic managerial simulation games}, journal = {Complexity}, volume = {15}, number = {4}, year = {2010}, pages = {31{\textendash}42}, publisher = {John Wiley \& Sons, Ltd}, author = {Yasarcan, Hakan} } @inbook {barlas2008comprehensive, title = {A comprehensive model of goal dynamics in organizations: setting, evaluation and revision}, booktitle = {Complex Decision Making}, year = {2008}, pages = {295{\textendash}320}, publisher = {Springer}, organization = {Springer}, author = {Barlas, Yaman and Yasarcan, Hakan} } @conference {barlas2007comprehensive, title = {A Comprehensive Model of Goal Dynamics in Organizations: Setting, Evaluation and Revision}, booktitle = {The 25th International System Dynamics Conference, Boston, MA, USA}, year = {2007}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2007/proceed/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2007/proceed/index.htm)}, author = {Barlas, Yaman and Yasarcan, Hakan} } @article {barlas2006goal, title = {Goal setting, evaluation, learning and revision: A dynamic modeling approach}, journal = {Evaluation and Program Planning}, volume = {29}, number = {1}, year = {2006}, pages = {79{\textendash}87}, publisher = {Elsevier}, author = {Barlas, Yaman and Yasarcan, Hakan} } @article {yasarcan2005generalized, title = {A generalized stock control formulation for stock management problems involving composite delays and secondary stocks}, journal = {System dynamics review}, volume = {21}, number = {1}, year = {2005}, pages = {33{\textendash}68}, publisher = {Wiley Online Library}, author = {Yasarcan, Hakan and Barlas, Yaman} } @conference {yasarcan2005stable, title = {Stable stock management heuristics when the outflow is proportional to the control stock}, booktitle = {The 23rd International System Dynamics Conference, Boston, MA, USA}, year = {2005}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2005/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2005/index.htm)}, author = {Yasarcan, Hakan and Barlas, Yaman} } @mastersthesis {yacsarcan2003feedback, title = {Feedback, delays and non-linearities in decision structures}, year = {2003}, school = {Bo{\u g}azi{\c c}i University}, type = {phd}, author = {Yasarcan, Hakan} } @conference {yasarcan2003general, title = {A general stock control formulation for stock management problems involving delays and secondary stocks}, booktitle = {The 21st International System Dynamics Conference, New York City, USA}, year = {2003}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2003/index.htm)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2003/index.htm)}, author = {Yasarcan, Hakan and Barlas, Yaman} } @conference {barlas2001method, title = {A Method For Finding Equilibrium Points of a Non-Linear Dynamic Model}, booktitle = {The 19th International System Dynamics Conference, Atlanta, Georgia, USA}, year = {2001}, publisher = {System Dynamics Society (http://www.systemdynamics.org/conferences/2001)}, organization = {System Dynamics Society (http://www.systemdynamics.org/conferences/2001)}, author = {Barlas, Yaman and Yasarcan, Hakan} } @conference {barlas1999bir, title = {Bir Benzetim Modeli {\"U}zerinde {\"O}SYS Sorunlar{\i}n{\i}n Analizi}, booktitle = {Cumhuriyetin 75. Y{\i}l{\i}nda {\"U}niversitelerimiz Sempozyumu ({\"U}niversite {\"O}{\u g}retim {\"U}yeleri Derne{\u g}i)}, year = {1999}, pages = {83{\textendash}112}, publisher = {Bo{\u g}azi{\c c}i {\"U}niversitesi Yay{\i}nevi}, organization = {Bo{\u g}azi{\c c}i {\"U}niversitesi Yay{\i}nevi}, author = {Barlas, Yaman and Yasarcan, Hakan} }